Laboratory for Cell-Free

Systems and Synthetic Biology

@ Northwestern University


Our research aims to develop cell-free biology as an enabling technology for biomanufacturing life-saving therapeutics, advanced materials, and sustainable chemicals, both quickly and on-demand. Specifically, we focus on designing, constructing, and modifying biological systems involved in protein synthesis and metabolism, with promise to advance new paradigms for synthetic biology.

  1. We aim to accelerate the construction of synthetic biomolecular machines making natural and unnatural biopolymers.

  2. We integrate fundamental science with technology development.

  3. We foster an inclusive, motivated, and creative culture which produces both world-class science and synthetic biology experts.


Mission Statement


December 2014 - Jewett Lab welcomes Do Soon Kim and Weston Kightlinger as PhD candidates.

September 2014 - Dr. Jewett honored with the Cole-Higgins Award for Excellence in Teaching

August 2014 - Dr. Jewett teaches at the Cold Spring Harbor Synthetic Biology course.

July 2014 - Dr. Jewett joins ACS Synthetic Biology as an Associate Editor.

May 2014 - Jessica Stark receives The Henry Luce Foundation - Clare Boothe Luce Graduate Fellowship, Society of Women Engineers Program

March 2014 - Niles West High School student Reyvin Reyes, mentored by Ben Des Soye, gets invited to the Illinois State Science fair and the Intel International Science and Engineering fair in Los Angeles. Ben also wins best mentor.

March 2014 - Ashty Karim selected as a Brady Fellow in ethics and civic life.

March 2014 - Dr. Jewett selected to organize the CSH Asia Synthetic Biology Meeting.

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